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Main Street Inn

Main Street Inn

Information

Open all day, everyday
573-880-7500
$129-$159 per night plus taxes
A pet friendly room is available
lat: 37.9824432 long: -90.0436106

Originally built in 1882, as the Meyer Hotel, the Main Street Inn B&B has long been one of Missouri’s finest bed and breakfast establishments. After recently undergoing an extensive year-long renovation, the new owners and innkeeper are thrilled to re-open the Main Street Inn B&B and welcome guests to what will be a truly wonderful experience.  Choose to stay in the:

  • Rendezvous Room, with private entrance
  • The Studio Room, with private entrance
  • La Rose Room
  • Felix Valle Room
  • Audubon Room
  • Trope Ricard Room, with private side porch
  • Suite Sainte Genevieve

All rooms feature fine linens, Wi-Fi, and all the grand amenities you would expect.  Savor a delicious breakfast served from 8:00 until 10:00.  You will truly have an unforgettable experience!

If you are looking for a relaxing and peaceful getaway, the Main Street Inn B&B is the perfect destination.

Nearby Attractions

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Nearby Trails

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Klondike Park River Access

lat: 38.5840552 long: -90.8200764
Fort Bellefontaine

lat: 38.827083 long: -90.214293
Red House Path

lat: 37.3008461 long: -89.5186713
Front Loop

lat: 38.82679 long: -90.21614
Lewis and Clark Nature Trail

lat: 38.77314 long: -90.4821
Trail of Tears Nature Trail

 Here, nine Cherokee Indian groups braved harsh winter conditions while crossing the Mississippi River in 1838-1839, marking a sorrowful chapter in American history. The park also has: shaded picnic sites, hiking and horse trails, opportunities to fish…

lat: 37.4388916 long: -89.480974
Trail of Tears Overlook

A breathtaking viewpoint overlooking the Trail of Tears State Park. Car access is available

lat: 37.4490937 long: -89.4764524
Chamoise to Klondike MO

lat: 38.70603 long: -91.73071
Jefferson Mounument

lat: 38.57877 long: -92.17348
Taylors Landing

A boat ramp to the beautiful Missouri River with a peaceful view of the river.

lat: 38.94831 long: -92.53559
Trail of Tears Access

A boat ramp that allows visitors to access the Trail of Tears

lat: 37.4539977 long: -89.4625079
Red Star Access Site

lat: 37.3156208 long: -89.5126263
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